Molecular recognition and catalysis with stoichiometric non-covalent interactions

MOLECULAR RECOGNITION AND CATALYSIS WITH STOICHIOMETRIC NON-COVALENT INTERACTIONS 

Molecular imprinting with covalent or stoichiometric non-covalent interactions 

Entry Template Polymerisable binding site Reference 

The usefulness of these novel amidine binding site monomers in molecular imprinting was demonstrated by their application in the preparation of polymers that were imprinted with optically active A -(4-carboxybenzoyl)-phenylglycine (15) the resulting materials could discriminate between the enantiomers of the template molecule with a values of up to 2.8 [12]. 

It is important to notice that the amidine moiety can act as a binding group and as a base at the same time. The importance of this dual nature will become apparent below, when we discuss the catalytic properties of imprinted polymers prepared using this functional group. 

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