Molecular Psychiatry

Now the use of molecular psychiatry of ascorbic acid in schizophrenia by Linus Pauling and others, where there seems to be some relationship to dopamine neurons, and finding that dopamine-dopaminergie neurons or receptors are present in twice the normal amount, makes this an intriguing... 

Pettigrew JW, Levine J and McClure RJ (2000). Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties Relevance for its mode of action in Alzheimer s disease and geriatric depression. Molecular Psychiatry, 5, 626-632. 

Kuratomi, G., Iwamoto, K., Bundo, M., Kusumi, I., Kato, N., Iwata, N., Ozaki, N. and Kato, T. (2008) Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins. Molecular Psychiatry, 13, 429-441. 

Laboratory of Molecular Psychiatry, Departments of Psychiatry and Pharmacology, Yale University School of Medicine, 34 Park Street, New Haven CT, 06508, USA ronald.duman yale.edu... 

S., Montecchi, E, Palermo, M., Pascucci, T., Puglisi-Allegra, S., Reichelt, K.-L., Conciatori, M., Marino, R., Quattrocchi C.C. Baldi, Zelante A., Gasparini P. and Keller E. (2001) Reelin gene alleles and haplotypes as a predisposing factor to Molecular Psychiatry 6 150-159 autistic disorder. 

Atypical Antipsychotic Effects in Schizophrenia. Molecular Psychiatry 12 (2007) 934-945. Kaddurah-Daouk and colleagues sampled the blood of 50 schizophrenia patients before and after drug treatment and found differences in metabolites that depended on the drug the patient received. 

Comings, David E., Radhika Gade, S. Wu, Connie Chiu, George Dietz, Donn Muhleman, G. Saucier, L Ferry, R. J. Rosenthal, H. R. LeSieur, L. j. Rugle, and P. MacMurray. 1997. "Studies of the Potential Role of the Dopamine D1 Receptor Gene in Addictive Behaviors." Molecular Psychiatry 2 44-56. 

Ebstein, Richard P.,and Robert H. Belmaker. 1997. "Saga of an Adventure Gene Novelty Seeking, Substance Abuse, and the Dopamine D4 Receptor (D4DR) Exon 111 Repeat Polymorphism." Molecular Psychiatry 2 381-84. 

Kotler, M., H. Cohen, Ronnen Segman, 1. Gritsenko, Lubov Nemanov, B. Lerer, I. Kramer, M. Zer-Zion, 1. KJetz, and Richard P. Ebstein. 1997. "Excess Dopamine D4 Receptor (DRW) Exon III Seven Repeat Allele in Opioid-Dependent Subjects." Molecular Psychiatry 251-54. 

LaHoste, G. J., J. M. Swanson, S. B. Wigal, C Glabe, T. Wigal, N. King, and J. L Kennedy. 1996. "Dopamine D4 Receptor Gene Polymorphism Is Associated with Attention Deficit Hyperactivity Disorder." Molecular Psychiatry 1 121-24. 

Malhotra, . ., M. Virkkunen, W. Rooney, M. Eggert, Markku Linnoila, and D. Goldman. 19%. "The Association Between the Dopamine D4 Receptor (DRD4) 16 Amino Acid Repeat Polymorphism and Novelty Seeking." Molecular Psychiatry 1 388-91. 

Molecular Psychiatry Research, Tokyo Institute of Psychiatry, Tokyo 156-8585, Japan... 

Duman RS, Heninger GR, Nestler EJ. 1994. Molecular psychiatry. Adaptations of receptor-coupled signal transduction pathways underlying stress- and drug-induced neural plasticity. J Nerv Ment Dis 182 692-700. 

Presidential Medal of Merit for weapons research made important discoveries in X-ray crystallography, electron diffraction, quantum mechanics, biochemistry, molecular psychiatry, nuclear physics, anesthesia, immunology, and evolution, written more than 400 articles, and created the century s most influential chemistry textbooks. He was the youngest person ever elected to the National Academy of Sciences and in 1954 had won the Nobel Prize in chemistry. 

Volpi S, Heaton C, Mack K et al. 2009. Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia. Molecular Psychiatry 14(11) 1024 1031. 

Laboratory for Molecular Psychiatry, RIKEN Brain Science Institute, Saitama 351-0198, Japan... 

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