Molecular packaging

Figure 6 Schematic representation of the molecular packaging and sequential metabolism used for brain targeting of neuropeptides. TRH-CDS (8) is included to provide a concrete illustration for the targetor (T), spacer (S), peptide (P), adjuster (A), and lipophilic (L) moieties. 

N. Bodor and L. Prokai, Molecular packaging peptide delivery to the central ner-... 

The solution described here is a complex molecular packaging strategy, in which the... 

Figure 15.40. CPK structures illustrating the sequential metabolism of the molecular package used for brain delivery cf a leucine enkephalin analog. See color insert.

The authors of Ref. [21] supposed, that in orientational drawing process of poly(metyl methacrylate) (PMMA) the following structure changes occur the transition to more equilibrium structure owing to molecular package improvement and internal stresses relaxation. The quantitative structural model absence not allows the authors of Ref [21] to give direct proofs of their suppositions. In Ref [22] such treatment was fulfilled on the example of extruded amorphous polyarylates DV and DF-10 with the cluster model of polymers amorphous state structure using [12, 23],... 

The similar concept regarding the stability of various structured polypropylenes, the activation energies required for the oxidative degradation depends evidently on the nucleation of substrates [74, 75]. For three sorts of polypropylene homopolymer (h-PP), random-copolymer (rc-PP) and impact-copolymer (ic-PP), the activation energies of photodegradation present a relevant sequence which particularizes the involvement of molecular packaging in the polymer volume ... 

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