Molecular imprinting schematic representation

Fig. 5-5. Schematic representation of the preparation procedure of molecular imprinted polymers (MIP).

Figure 1.21 Schematic representation of the strategy of molecular chiral imprinting of a sol-gel matrix using a chiral template and suitable achiral silanes. (Reproduced from ref. 48, with permission.)...

Scheme 15.1 Schematic representation of the molecular imprinting process.

Scheme 10.5 Synthesis of the UPy reversibly unfolding modular cross-linker. Scheme 15.1 Schematic representation of the molecular imprinting process.

Fig. 11 Schematic representation of the molecular imprinting of trypsin using a polymerizable inhibitor as an anchoring monomer. The enzyme is put into contact with the anchoring monomer and co-monomers (a) polymerization is conducted (1) a cross-linked polymer is molded around the substrate binding site (b) the enzyme is removed (2), revealing a specific recognition site with inhibitory properties (c). Reproduced with permission from [108], Copyright 2009 American Chemical Society...

Fig. 12 (a) Schematic representation of the preparation of a molecularly imprinted polymer with immobilized Au nanoparticle and the detection of an analyte upon selective swelling of the MIP. Reprinted with permission from [123]. Copyright (2004) American Chemical Society, (b) Schematic representation of Au-MIP/MIP-coated SPR sensor chip. Reprinted with permission from [124]. Copyright (2005) American Chemical Society... 

FIGURE 9. Schematic representation of the molecular imprint approach by sacrifical elimination of an organic fragment from a hybrid organic-inorganic material... 

Fig. 3.1. A highly schematic representation of the molecular imprinting process. A monomer mixture with ehemical functionality complementary to that of the template is allowed to form solution adducts through the complementary interacting functionalities (reversible covalent or non-covalent interactions). Polymerisation in the presence of a cross-linking agent, followed by removal of the template, leads to the defining of recognition sites of complementary steric and functional topography to the template molecule.

Fig. 3.2. A schematic representation of the molecular imprinting pre-arrangement phase (corresponding to 2 in Fig. 3.1), here using ()-nicotine as the template and carboxylic acid containing functional monomers. In this case a total of five states of complexation are proposed I, non-complexed template II, weak single point interaction III, strong single point interaction IV, combination of weak and strong interactions V, higher order complexes e.g. monomer interactions with template-template self-association complexes, higher monomer solvation levels.

Figure 7.8 A schematic representation of the preparation of molecularly imprinted polymers [19]. (a) Functional monomer MAA (1) is mixed with print molecule, here theophylline (2), and EDMA, the cross-linking monomer, in suitable solvent. MAA is selected for its ability to form hydrogen bonds with a variety of chemical functionalities of the print molecule. (6) The polymerization reaction is started by addition of initiator (2,2 -azobis(2-methylpropionitrile), AIBN). A rigid insoluble polymer is formed, Imprints , which are complementary to the print molecule in both shape and chemical functionality, are now present within the polymeric network, (c) The print molecule is removed by solvent extraction. The wavy line represents an idealized polymer structure but does not take into account the accessibility of the substrate to the recognition site,...

Figute 2. Schematic representation of die molecular imprinting protocol. 

Fig. 6 Schematic representation of a molecular imprinting with template (TSA) b imprinted recognition site following template removal c,d catalysis...

FIGURE 51.14 Schematic representation of a molecular imprinting process. (Reprinted from/nf. J. Pharm., 195(1-2), Allender, C.J., Richardson, C., Woodhouse, B., Heard, C.M., and Brain, K.R., Pharmaceutical applications for molecularly imprinted polymers, 39-43. Copyright 2000, with permission from Elsevier.)... 

Figure 18.1 Schematic representation of molecular imprinting (a) Formation of a template-monomer complex, (b) formation of pol3oner matrix after polymerization step, and (c) formation of recognition site after template removal from the polymeric matrix.

Scheme 13 Schematic representation of molecularly imprinted polymer preparation for P-17 and subsequent use to catalyze the aldol condensation between acetophenone, 29, and benzaldehyde, 30.

Figure 21 Schematic representation of molecular imprinting of 9-ethyl adenine (9EA) using 5,10,15-tris(4-isopropylphenyl)-20-(4-methacyloloxyphenyl)porphyrin zinc (II) complex and methacrylic acid as a functional monomer.

Hgure 3 Schematic representation of molecular imprinting process T, template A, mixing and prearrangement B, polymerization C, template washing and Soxhiet extraction. (Reproduced with permission from Rao et al. (2004) Trends in Analytical Chemistry 23 24.)... 

Fig. 2.12 Schematic representation of the molecularly imprinting process the formation of reversible interactions between the template and polymerizable functionality may involve one or more of the following interactions (A) reversible covalent bond, (B) covalently attached polymerizable binding groups that are activated for nrai-covalent interaction by template cleavage, (C) electrostatic interactions, (D) hydrophobic or Van der Waals interactirais, (E) co-ordination with a metal center each kind of interaction occurs with complementary functional groups or structural elements of the template, (a-e), respectively. A subsequent polymerization in the presence of crosslinker(s) results in the formation of an insoluble matrix in which the template sites reside. Template is then removed from the polymCT through disruptirai of polymer-template interactions, and extraction from the matrix. (Reproduced fiom Ref. [97] with the permission of Wiley)...

Fig. 14 (a) Molecular structures of receptors employed in the work, (b) Schematic representation of fluorescent ion-imprinted mesoporous silica. Reprinted with permission from [62]... 

Fig. 1. Schematic representation of Non-Covalent Molecular Imprinting Process. Adapted from Liu Z. et al., 2010.

Figure 33 Schematic representation of (a) molecular imprinting and (b) removal of paracetamol from paracetamol-imprinted PPy-modified pencil graphite electrode. Reproduced with permission from Ozcan, L. Sahin, Y. Sens. Actuators, S2007,127(2), 362-369. ...

FIGURE 4.5 Schematic representation of the preparation of molecularly imprinted polymers. 

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