Molecular biology, and drug

Computational Molecular Biology and Drug Design Group, Division of Biochemistry and Molecular Biology, John Curtin School of Medical Research, Australian National University, Canberra, ACT 2601, Australia... 

Browne, M. J. Thurlby, P. L. Genomes, Molecular Biology and Drug Discovery, Academic London, 1996. 

Krallinger M, Erhardt RA, Valencia A. Text-mining approaches in molecular biology and biomedicine. Drug Disc Today 2005 10 439-45. 

The book is separated into five major sections One short section on general aspects of spectroscopy, molecular biology and data evaluation is followed by an introduction into the NMR of commonly encountered classes of biomolecules. Thereafter, recent developments in spectroscopic techniques are highlighted. The next section describes experiments and practical aspects useful for the characterization of protein-ligand interactions. The final section presents an account on strategies for drug development using NMR written by experts from pharmaceutical industry. 

Modern techniques of molecular biology and electrophysiology can identify multiple subtypes of calcium and potassium channels. One way in which such subtypes may differ is in sensitivity to drug effects, so drugs targeting specific channel subtypes may be developed in the future. 

Lynch D. R. and Guttmann R. P. (2001). NMDA receptor pharmacology perspectives from molecular biology. Curr. Drug Targets 2 215-231. 

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