Moffatt

Bunton C A, Moffatt J R and Rodenas E 1982 Abnormaiiy high nucieophiiicity of miceiie-bound azide ion J. Am. Chem. Soc. 104 2653-5... 

The widely used Moifatt-Pfltzner oxidation works with in situ formed adducts of dimethyl sulfoxide with dehydrating agents, e.g. DCC, AcjO, SO], P4O10, CCXTl] (K.E, Pfitzner, 1965 A.H. Fenselau, 1966 K.T. Joseph, 1967 J.G. Moffatt, 1971 D. Martin, 1971) or oxalyl dichloride (Swem oxidation M. Nakatsuka, 1990). A classical procedure is the Oppenauer oxidation with ketones and aluminum alkoxide catalysts (C. Djerassi, 1951 H. Lehmann, 1975). All of these reagents also oxidize secondary alcohols to ketones but do not attack C = C double bonds or activated C —H bonds. 

W. G. Moffatt, The Handbook ofBinay Phase Diagrams, Genium Publishing Corp., Schenectady, N. Y., 1989, updated. 

W. G. Moffatt, G. W. Pearsall, andj. Wulff, The Structure and Properties of Materials, Vol. 1, John Wiley Sons, Inc., New York, 1964. 

A. L. Boehman, S. Niksa, and R. J. Moffatt,H Comparison of Rate Earnfor CO Oxidation OverPt on Mlumina, SAE 930252, Society of Automotive Engineers, Warrendale, Pa., 1993. 

J. G. Moffatt, Eleventh National Medicinal Chemistry Symposium, Universite Laval, Quebec, Canada, Abstracts of Papers, pp. 15a-h, June, 1968. 

The facile and selective oxidation of both primary and secondary hydroxy groups with certain nucleotides led Pfitzner and Moffatt (48) to explore the scope of the carbodiimide-methyl sulfoxide reagent with steroid and alkaloid alcohols. Relatively minor differences were apparent in the rate of oxidation of epimeric pairs of 3- and 17- hydroxy steroids whereas the equatorial lLx-hydroxyl group in several steroids was readily oxidized under conditions where the axial epimer was unreactive [cf. chromic oxide oxidation (51)]. 

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