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Modified-release products Enteric coatings

Intravenous administration, or the use of enteric-coated formulations or modified-release products all appear to reduce the risk both of bleeding and more particularly of erosions/ulceration. However, because of the indirect effect noted above, such formulations do not eliminate the risk, although they may reduce the incidence of... [Pg.20]

The pharmaceutical and biological availability of eight commercial furose-mide preparations was compared including two products with modified release properties [67], an enteric-coated tablet and a sustained-release preparation, in the form of a capsule containing diffusion pellets [28], A correlation between the rate of dissolution of different techniques and the area under the plasma concentration time curve was documented. The sustained-release preparation and the enteric-coated formulation clearly showed different pharmacokinetic behavior compared with conventional tablets. Although the literature mentions the maximal absorption at pH 5.5, the modified release formulations only showed a relative bioavailability of 80%. [Pg.32]


See other pages where Modified-release products Enteric coatings is mentioned: [Pg.393]    [Pg.922]    [Pg.363]    [Pg.75]    [Pg.349]    [Pg.98]    [Pg.11]    [Pg.372]    [Pg.112]    [Pg.640]    [Pg.1]    [Pg.276]    [Pg.503]    [Pg.640]    [Pg.14]    [Pg.359]    [Pg.370]    [Pg.627]    [Pg.2689]   


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Enteral

Enteric

Enteric coat

Enteric coated

Enteric coatings

Enteric-coated products

Entering

Modified-release products

Product release

Release coatings

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