Mitochondrion-like organelle

Putignani L et al. (2004) Characterization of a mitochondrion-like organelle in Cryptosporidium parvum. Parasitology 129 1-18... 

Williams and Keeling 2002). We also suggest that this close association of the mitochondrion-like organelle and endomembrane system facilitates the assembly of cytosolic Rlil, the only known essential FeS protein for yeast viability (Iill et al. 2005 reviewed in Tachezy and Dolezal 2007). These data are consistent with previous hypotheses that the primary function of the mitochondrion-like organelle in C. parvum is the assembly of FeS clusters in order to provide mature FeS proteins to all cellular compartments, including the cytosol, mitochondrion, and nucleus. 

Fig. 4 Transmission electron microscopy of a longitudinal section of the posterior end of a Cryptosporidium parvum sporozoite showing immunogold localization of pyruvate NADP+ oxidoreductase (CpPNO). The mitochondrion-like organelle ( ) is posterior to the nucleus, and lies between the nucleus and the CB. It is labeled by mitochondrion-specific 15-nm gold anti- particles. Small -nm gold goat anti-CpPFO particles (arrows) show the localization of CpPNO. There are no 6-nm particles localized within the mitochondrion-like organelle (reprinted from Fig. 12 of Ctrnacta et al. 2006 with permission of the publishers)...

Nasirudeen AM, Tan KS (2004) Isolation and characterization of the mitochondrion-like organelle from Blastocystis hominis.J Microbiol Methods 58 101-109 Painter HJ, Morrisey JM, Mather MW, Vaidya AB (2007) Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum. Nature 446 88-91 Perkins GA, Song JY, Tarsa L, Deerinck TJ, Ellisman MH, Frey TG (1998) Electron tomography of mitochondria from brown adipocytes reveals crista junctions. J Bioeneerg Biomembr 30 431-432... 

Petry F, Harris JR (1999) Ultrastructure fractionation and biochemical analysis of Cryptosporidium parvum sporozoites. Int J Parasitol 29 1249-1260 Putignani L, Tait A, Smith HV, Horner D, Tovar J, Tetley L, Washing JM (2004) Characterization of a mitochondrion-like organelle in Cryptosporidium parvum. Parasitol 129 1-18... 

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