Minimal Modeling Using Hypothesis Testing

The agreement between the model and the data might be formalized using various statistical tests, one of the most common of which is the x2 test. The x2 test 

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In an attempt to better understand the role of receptor internalization, a minimal model has been developed using hypothesis testing [10]. The model is based on experimental data on autophosphorylation of the IR. Upon addition of insulin to intact adipocytes, the IR rapidly autophosphorylates with an overshoot peak before t = 0.9 min, and then slowly declines to a quasi-steady state at around 15 min. 

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