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Kosugi-Migita-Stille coupling

Reaction with Organotin Reagents (Migita-Kosugi-Stille Coupling) 656... [Pg.653]

STILLE CROSS-COUPLING (MIGITA-KOSUGI-STILLE COUPLING)... [Pg.438]

The palladium-catalyzed coupling of organotin compounds with organic hahdes is a powerful method for carhon-carhon bond formation. This procedure is called Migita-Kosugi-Stille coupling [4, 5] and has been widely used for organic synthesis... [Pg.653]

When 1,2-diiodoalkenes were subjected to the coupling reaction monofunctionalization occurred successfully and the new C-C bond was formed preferentially at the less hindered iodide [160]. Migita-Kosugi-Stille coupling occurs preferably at iodide and bromide leaving fluoride intact - treatment of fluoroethenyl iodide [161] and bromide [162] with arylstannane in the presence of palladium catalyst afforded the corresponding ethenyl fluoride products, respectively. [Pg.655]

Acid hahdes can also be used in Migita-Kosugi-Stille coupling in this C-C bond formation fhe corresponding ketone is produced. Subjection of a benzoyl chloride derivative prepared in situ to cross-couphng with a vinylstannane provided the desired vinyl ketone which was successfully transformed to a potent COX-2 inhibitor (Scheme 12.99) [201],... [Pg.665]

Attention has been paid to P-C bond cleavage of organophosphorus compounds not only for synthetic application but also for understanding of a deactivation process in Mizoroki-Heck reaction [161], Migita-Kosugi-Stille coupling [162], or hydroformylation [163]. Simultaneous arylation originated from triarylphosphine is sometimes involved (Eq. 3.42). [Pg.169]

Also referred sometimes as the Migita-Kosugi-Stille coupling. [Pg.160]

See other pages where Kosugi-Migita-Stille coupling is mentioned: [Pg.228]    [Pg.217]    [Pg.392]    [Pg.121]    [Pg.134]    [Pg.217]    [Pg.116]    [Pg.266]    [Pg.643]    [Pg.653]    [Pg.653]    [Pg.655]    [Pg.657]    [Pg.658]    [Pg.659]    [Pg.659]    [Pg.661]    [Pg.663]    [Pg.665]    [Pg.667]    [Pg.669]    [Pg.687]    [Pg.208]    [Pg.700]    [Pg.1321]    [Pg.88]    [Pg.244]    [Pg.1321]    [Pg.448]   
See also in sourсe #XX -- [ Pg.68 ]

See also in sourсe #XX -- [ Pg.635 , Pg.643 , Pg.653 ]



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Migita

Migita-Kosugi-Stille cross-coupling

Stille coupling

Stille-Kosugi coupling

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