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Midbrain dopaminergic neurons, role

Persephin (PSPN) has been shown to promote the survival of basal forebrain neurons including both cholinergic neurons. Moreover, it supports midbrain dopaminergic neurons. PSPN is expressed in the striatum, consistent with its role as a target-derived trophic factor for these cells. [Pg.481]

Peng GS et al (2005) Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures role of microglia. Brain Res Mol Brain Res 134( 1) 162—169... [Pg.53]

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