Microwave-assisted organic synthesis multimode reactor

Stadler, A., Yousefi, B.H., Dallinger, D., Walla, P., VanderEycken, E., Kaval, N. and Kappe, C.O., Scalability of microwave-assisted organic synthesis from single-mode to multimode parallel batch reactors, Org. Process Res. Dev., 2003,7, 707. 

Other microwave-assisted parallel processes, for example those involving solid-phase organic synthesis, are discussed in Section 7.1. In the majority of the cases described so far, domestic multimode microwave ovens were used as heating devices, without utilizing specialized reactor equipment. Since reactions in household multimode ovens are notoriously difficult to reproduce due to the lack of temperature and pressure control, pulsed irradiation, uneven electromagnetic field distribution, and the unpredictable formation of hotspots (Section 3.2), in most contemporary published methods dedicated commercially available multimode reactor systems for parallel processing are used. These multivessel rotor systems are described in detail in Section 3.4. 

In the literature, first microwave-assisted experiments on organic synthesis employed multimode household microwave ovens [12,13]. More recently, the use of microwave reactors for chemical syntheses has become more advanced, and, at the moment, some chemical journals specializing in organic chemistry intend to refuse manuscripts in which experiments were carried out in a domestic microwave oven (even including ovens with... 

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