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Microwave-assisted organic synthesis multicomponent reactions

Microwave-assisted organic synthesis may also be used for carrying out the multicomponent reactions of ketones and 1,2-diamines [20, 21, 92, 100]. For example, the three-component reaction of o-PDA 1 with acetoacetic acid ethyl ester 83 and a series of aromatic and heteroaromatic aldehydes 84 proceeds under microwave irradiation with very high yields of diazepines 85 (up to 95%) [100]. Reaction of 2 equiv of cyclohexanone 86 with o-PDA 1 was also realized in a microwave field on a basic alumina surface in 4 min [92] (Scheme 4.27). [Pg.161]

Westman J (2004) Speed and Efficiency in the Production of Diverse Structures Microwave-Assisted Multicomponent Reactions. In LidstrOm P, Tierney JP (eds) Microwave-Assisted Organic Synthesis. Blackwell, Oxford, p 102... [Pg.98]

Microwave-assisted organic synthesis Cross-coupling and multicomponent reactions 13COC474. [Pg.219]

Bremner WS, Organ MG (2007) Multicomponent reactions to form heterocycles by microwave-assisted continuous flow organic synthesis. J Comb Chem 9(1) 14—16... [Pg.195]

See other pages where Microwave-assisted organic synthesis multicomponent reactions is mentioned: [Pg.31]    [Pg.32]    [Pg.76]    [Pg.483]    [Pg.31]    [Pg.32]    [Pg.32]    [Pg.367]    [Pg.181]    [Pg.421]    [Pg.181]    [Pg.181]    [Pg.443]    [Pg.378]    [Pg.208]   


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Microwave organic synthesis

Microwave synthesis

Microwave-assisted

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Microwave-assisted organic synthesis

Multicomponent reaction reactions

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