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Microsomal p-Hydroxylation of Anilines by Alcohols

Sabljic has investigated a series of aliphatic alcohols which inhibit the p-hydroxylation of anilines by cytochrome P-450.For the 20 alcohols studied, it was found that an inverse relation exists between the activity and the Addition of the Xpc index yields a satisfactory QSAR equation  [Pg.388]

Sabljic, A. and Protic-Sabljic, M. (1983). Quantitative Structure-Activity Study on the Mechanism of Inhibition of Microsomal p-Hydroxylation of Aniline by Alcohols. Mol.Pharm., 23,... [Pg.640]

Amic, D., Lucic, B., Nikolic, S., and Trinajstic, N. (2001) Predicting inhibition of microsomal p-hydroxylation of aniline by aliphatic alcohols a QSAR approach based on the weighted path numbers. Croat. Chem. Acta 74, 237-250. [Pg.520]

Basak SC, Gute BD (1997) Use of graph theoretic parameters in predicting inhibition of microsomal hydroxylation of anilines by alcohols a molecular similarity approach. In Johnson BL, Xintaras C, Andrews JS (eds) Proceedings of the international congress on hazardous waste impact on human and ecological health. Princeton Scientific, Princeton, NJ, p 492... [Pg.80]

See other pages where Microsomal p-Hydroxylation of Anilines by Alcohols is mentioned: [Pg.388]    [Pg.388]    [Pg.498]   


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Alcohol aniline

Alcoholic hydroxyl

Aniline hydroxylation

Hydroxylation of Aniline by Alcohols

Microsomal

Microsomal microsomes

Microsomes

Of aniline

P- aniline

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