Microscreen assay

Rossman TG, Molina M, Meyer L, et al. 1991. Performance of 133 compounds in the lambda prophage induction endpoint of the Microscreen assay and a comparison with IS. typhimurium mutagenicity and rodent carcinogenicity assays. Mutat Res 260 349-367. 

Another assay which indirectly measures DNA damage (or halting of the replication fork) is the induction of prophage in the Microscreen assay this eventually measures the ability of an agent to induce the SOS system in E. coli. Reversion assays depend on mutations of a specific type at specific sites in the DNA, and require different tester strains for each type of reversion. 

Houk VS, DeMarini DM. 1988. Use of the microscreen phage-induction assay to assess the genotoxicity of 14 hazardous industrial wastes. Environ Mol Mutagen 11 13-29. 

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See also in sourсe #XX -- [ ]

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