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Microparticles drug release control

Keywords. Controlled drug release, Hydrogels, Microparticles, Nanoparticles, Niosomes, Tablets, Transdermal... [Pg.45]

Liu C-S, Desai KGH, Meng X-H, Cheng X-G (2007) Sweet potato starch microparticles as controlled drag release carriers preaparation and in vitro drug release. Drying Technol 25 689-693... [Pg.62]

Palmieri, G.E. Wehrle, P. Stamm, A. Evaluation of spraydrying as a method to prepare microparticles for controlled drug release. Drug. Dev. Ind. Pharm. 1994, 20, 2859-2879. [Pg.1655]

Drug release from biodegradable polymer microparticles is determined by the polymer degradation kinetics, structural features of the microparticles, and distribution of the drugs within the particle matrix. The ultimate goal of microparticle systems in the controlled drug delivery is to achieve readily tunable release profiles, which has been pursued in various perspectives. [Pg.2322]

CyDs to Control Drug Release Profile 15.3.3.1 Microparticles... [Pg.442]

In 1998, Avnir and coworkers patented the interfacial polymerization process in which the mild sol-gel production of silica glass is combined with emulsion chemistry to form sol-gel spherical microparticles in place of irregular granules. In brief, the emulsion droplets provide a microreactor environment for the hydrolysis and condensation reactions of Si alkoxides. All sorts of molecules can be entrapped and stabilized in similar ceramic microparticles with broad control over the release rate for a range of applications (such as drug delivery, release of specialty chemicals and cosmeceutical/ nutraceutical, and beyond, Figure 18.1), with no need for reformulation for different molecules. [Pg.330]

Another parameter affecting EHDA is polymer concentration. Enayati et al. investigated the effect of polymer concentration on the drug release rate of microparticles. They found that the rate of release could be effectively controlled by this parameter. Eigure 22.28 shows that as concentration decreased, the size of the particles decreased and the surface-to-volume area increased, which increased the rate of drug release. ... [Pg.432]

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See also in sourсe #XX -- [ Pg.442 ]



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