Micromixer cream formation

Altvater, M., Rietz, R., Neubeet, R., Micromixer based formation of emulsions and creams for pharmaceutical applications, in Proceedings of the 4th International Conference on Microreaction Technology, IMRET 4, pp. 467 77 (5-9 March 2000), AIChE Topical Conf Proc., Atlanta, USA. 

Cream Formation in Micromixers Targeting a Reduction in Emulsifiers and Preservatives 371... 

Compared with a laboratory shaker (8 pm mean droplet size and 5 pm standard deviation of the size distribution), dear advantages of the micromixer-based cream formation were revealed, i.e. smaller droplets and a narrower size distribution (Figure 22.7). 

The micromixer-based continuous formation of a hydrophflic cream for dermal application was studied by Schiewe et al. [16]. In addition to showing the feasibility and exploring the advantages compared with a conventional laboratory shaker, the investigations also targeted lowering the amount of emulsifiers and preservatives required since they can be the source of allergic reactions. 

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See also in sourсe #XX -- [ ]

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