Microgravimetric quartz crystal microbalance

Patolsky, K, Zayats, M., Katz, E., and Willner, I. (1999) Precipitation of an insoluble product on enzyme monolayer electrodes for biosensor applications Characterization by faradaic impedance spectroscopy, cyclic voltammetry, and microgravimetric quartz crystal microbalance analyses. Anal. Chem. 71, 3171-3180... 

FIG. 7.30 Electronic and optical transduction of the formation of antigen-antibody affinity complexes on transducers (A) Amperometric transduction at an electrode (R /K Is a redox label In the electrolyte solution). (B) Transduction by faradic Impedance spectrosco . (C) Microgravimetric quartz crystal microbalance (QCM) transduction in the presence of a piezoelectric quartz crystal. (D) Surface plasmon resonance transduction. 

A ConA biosensor based on a microgravimetric quartz crystal microbalance (QCM) has been developed in a sandwieh-type experiment, using mannoside-stabilized GNPs as a signal amphfier. The addition of ConA over gold QCM electrode... 

Different electronic transduction methods to probe DNA recognition events on surfaces will be addressed in the present account. These include electrochemical transduction means such as amperometry, faradaic impedauce spectroscopy or chronopotentiometry, and microgravimetric, quartz-crystal-microbalance (QCM) measurements. 

E. Patolsky, M. Zayats, E. Katz, I. WiUner, Precipitation of an Insoluble Product on Enzyme Monolayer Electrodes for Biosensor Appbcations Characterization by Earadaic Impedance Spectroscopy, Cycbc Voltammetry, and Microgravimetric Quartz Crystal Microbalance Analysis. Anal. Chem., 71 (1999) 3171-3180. 

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