Microgels hydrolytic

Fig. 32. Relation between the residual unsaturation ( ) IR-spectroscopy, (O) hydrolytic degradation resp. the titratable acid groups of microgels (a) and their EUP-content [132]. EUP(MA+HD),Mn 1640, c/t 67/33, EUP/S varied, W/M 20.

The following two sections will describe how these materials have been exploited so far to improve the activity of systems, previously developed as a bulk or newly designed, creating molecularly imprinted microgels with hydrolytic activity or C-C bond formation capability. 

The first example that describes imprinted catalytic microgels was reported in 2004 by Resmini et al. [71], which described the synthesis of soluble acrylamide-based microgels with hydrolytic activity towards 4-acetamidophenyl 4-nitrophenyl carbonate (102). The imprinting strategy was based on the corresponding phosphate TSA (103). Literature data demonstrated that arginine (104) and tyrosine (105) are... 

Our group has demonstrated that the catalytic properties of immobilized enzymes can be manipulated by the temperature-dependent swelling behavior of the microgel. The hydrolytic activity of adsorbed and native P-D-glucosidase was determined as a function of temperature. Desorption of immobilized enzyme upon... 

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