Single-channel microchips

Wang, J., M. Pumera, M. P. Chatrathi, A. Escarpa, M. Musameh, G. Collins, A. Mulchandani, Y. Lin, and K. Olsen. Single-channel microchip for fast screening and detailed identification of nitroaromatic explosives or organophosphate nerve agents. Anal. Chem. 74, 1187-1191 (2002). 

Wang, J., et al. "Single-Channel Microchip for Fast Screening and Detailed Identifcation of Nitroaromatic Explosives or Organophosphate Nerve Agents." Analytical Chemistry 74 (2002), 1187-1191. 

The microchips are coupled to an SIA system for fully automated determination of MSG. The system is constructed with a syringe pump, a 10-multiposition valve, an enzymatic microchip, and a fluorescence detector. The inlet capillary of the single-channel microchip is connected to a 10-position valve, but in this case, only four ports are used (only beads, sample, waste, and microchip position). The whole system is controlled by a computer using software developed in-house. The fluorescence of the NADH peak is recorded by a chart recorder. 

Kawai, T., et ah, 2010. Microchip electrophoresis of oligosaccharides using large-volume sample stacking with an electroosmotic flow pump in a single channel. Anal. Chem. 82 (15), 6504-6511. Available at http //www.ncbi.nkn.nih.gov/pubmed/20586466. 

Kikutani, Y., Hisamoto, H., Tokeshi, M., Kitamori, T, Fabrication of a glass microchip with three-dimensional channel network and its application to a single-chip combinatorial synthetic reactor, in Ramsey, J. M., VAN den Berg, A. (Eds.), Micro Total Analysis Systems, pp. 161-162, Kluwer Academic Publishers, Dordrecht (2001). 

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