Microbiology peptides, bacterial

At the present time, the market share of commercial hyaluronan of bacterial origin is significantly higher than the products extracted from animal sources, the reason being that microbiological synthesis affords a significantly higher yield the fermentation of the strain Streptococcus sp. resulted in a polysaccharide concentration of 5-6 g per 11 of culture medium. Comparatively, the yield of HA in the extraction from the chicken combs is from 0.5 g to 6 g per 1 kg of raw material. Because the purification of bacterial HA from proteins and peptides is easier, so it is therefore easier to obtain the HA product with a molecular mass of 1 million Da and protein content of less than 0.05%. The HA products from... 

Both equations confirm that AMP belonging to that set, act through electrostatic interactions with bacterial membrane [15], However, a good cannot capture the quality of an activity model because the intrinsic experimental error in microbiological tests, due to serial dilutions, is not considered. It is more correct to talk about activity classes, and the goodness of a QS AR model must be judged in terms of its ability to discriminate among very active, active and non-active peptides. For this reason, MIC (minimum inhibitory concentration expressed in pM) values of 0.3 and 1.8 must be considered as peptides with the same activity. To evaluate the models, we divided the peptides in classes of MIC as shown in Table 1. The 5 classes have similar dimension. 

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