Micellar bolaamphiphiles

Figure 5.12 Electron micrograph of a monolayered micellar fibre (diameter 2.5 0.4 nmj made of the bolaamphiphile 9 at pH 10. Negatively stained with phoshotungstate.

A bolaamphiphile with two central secondary amide groups and terminal lysine amino groups assemble to uniform, long tubules. The inner diameter is 50 nm, the membrane thickness 4.4 nm. These tubules were quantitatively isolated in solid form by lyophilization. Shorter bolaamphiphiles give micellar rods (Figure 9.5.2). 

Figure 9.5.2 Electron micrographs of vesicular tubules and micellar rods made of single-chain lysine-amino bolaamphiphiles. (From Fuhrhop et al., 1993.)...

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