Hepatitis micafungin

Hepatic effects Laboratory abnormalities in liver function tests have been seen in healthy volunteers and patients treated with micafungin. 

Liver Hepatitis associated with micafungin has been reported in a preterm infant [96 ]. 

King KY, Edwards MS, Word BM. Hepatitis associated with micafungin use in a preterm infant J Perinatol 2009 29 320-2. 

Observational studies The safety of micafungin as an empirical antifungal therapy in 388 Japanese patients with haematologic disorders and neutropenia has been evaluated [71 ]. Micafungin-associated adverse effects were observed in 56 patients (14.4%) and serious adverse effects were observed in six patients (1.5%). The most common adverse effects were hepatic fxmction abnormalities (9.8%) followed by skin disorders (3.1%), renal and xuinary abnormalities (1.2%) and other adverse effects (4.4%). 

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