Meyer, Hans

Submitted by Hans-Ulrich Reissig, Ingrid Reichelt, and Thomas Kunz.1 Checked by Lawrence Snyder and Albert I. Meyers. 

Professor Meyer was born at Dorpat, Estonia, on September 29, 1883, the elder son of Hans Horst Meyer—who held the chair of experimental pharmacology at the University of Vienna and formulated the modern theory of narcosis known as the Overton-Meyer theory. Two years later, his father became professor at Marburg/Lahn, and it was in this city that Kurt H. Meyer had his early education. The scholarly atmosphere in which he matured, where chemistry and medicine were always very much in the foreground, was to influence him throughout his lifetime. From his father, he inherited his desire for scientific study and research, and from his mother, his taste for the fine arts. His younger brother became a famous heart-surgeon. 

Here only a general review of methods and manipulations has been given, in so far as they are employed in the preparative exercises. The comprehensive and thorough works of Lassar-Cohn, Hans Meyer, and Houben-Weyl should be consulted for special requirements. 

In the four volumes of Die Methoden der organiscken Chemie of Houben and Weyl, all the methods used in organic laboratories are systematically collected and described, whilst the comprehensive book by Hans Meyer, Analyse und Konstitutionsermittlung organischer Verbindungen, is more concerned with analytical requirements. 

For WGS, commercial catalysts are only operated up to 550 °C and no catalysts are available for higher temperatures, because adverse equilibrium conversion makes the process impractical in the absence of a CO2 sorbent. Han and Harrison [38] have shown that, at 550 °C, dolomite and limestone have a sufficiently high WGS activity. For SMR a conventional Ni SMR catalyst is used in a 1 1 ratio with CaO [30]. Meyer et al. [32] have also used a Ni-based catalyst in combination with limestone and dolomite, and achieved CH4 conversions of 95% at 675 °C while the CH4 conversion at equilibrium was 75%. 

The authors beg to acknowledge assistance received directly and indirectly from well-known text-books by the following authors—Adams and others, Barnett, Barrowcliff and Carr, Cain, Cain and Thorpe, Cohen, Elbs, Fiertz-David, Fischer, Gattermann, Henderson, Knecht and Hibbert, Lassar-Cohn, Hans Meyer, Meyer-Jacobson, Meyer-Tingle, Perkin, F. M., Sudborough and James, and Ullmann. 

Hans-Wilhelm Meyers Deichmannhaus am Dom B ahnho fs vorp 1 a tz 1 50667 Koln Germany... 

The first chemical clue relating the structure of anesthetics to their potency was discovered in 1899 by a pharmacologist, Hans Horst Meyer, and an anesthetist, Charles Ernst Overton. Working independently, Meyer and Overton noted a strong correlation between the polarity of a compound and its potency as an anesthetic. They expressed polarity as the oil/gas partition coefficient, while anesthetic potency was expressed as the partial pressure in atmospheres. Figure 11.10 is a Meyer-Overton correlation for 18 anesthetics used on mice. Note that olive oil is used, and it has become the most commonly used reference solvent. 

Many prominent colleagues who have worked in computational chemistry have passed away since about the time this book series began. These include (in alphabetical order) Jan Almlof, Russell J. Bacquet, Jeremy K. Burdett, Jean-Louis Calais, Michael J. S. Dewar, Russell S. Drago, Kenichi Fukui, Joseph Gerratt, Hans H. Jaffe, Wlodzimierz Kolos, Bowen Liu, Per-Olov Lowdin, Amatzya Y. Meyer, William E. Palke, Bernard Pullman, Robert... 

R. L. Lipnick, Trends Pharmacol. Sci., 10, 265 (1989). Hans Horst Meyer and the Lipoid Theory of Narcosis. 

Lipnick RL. Hans Horst Meyer and the lipoid theory of narcosis. Trends Pharmacol Sci 1989 10 265. 

QSAR studies date back to the nineteenth century. In 1863, A. F. A. Cros at the University of Strasbourg observed that toxicity of alcohols to mammals increased as the water solubility of the alcohols decreased. In the 1890s, Hans Horst Meyer of the University of Marburg and Charles Ernest Overton of the University of Zurich, working independently, noted that the toxicity of organic compounds depended on their lipophilicity. 

CEO s foreword the report contains a foreword by Rolf A. Meyer (Chairman and CEO), and an overview of achievements and challenges from Hans-Ulrich Muller (Executive Vice-President Law and Environment) and Peter Donath (Global Vice-President Environment, Health and Safety). 

McManus JD, Brune DC, Han J, Sanders-Loehr J, Meyer TE, Cusanovich MA, Tollin G, Blankenship RE (1992) J Biol Chem 267 6531... 

The classic experiments were those performed by Ernest Overton and Hans Meyer at the turn of the twentieth century, where tadpoles were placed in solutions containing alcohols of increasing hydrophobicity. They found a correlation between the concentration of the alcohol required to cause cessation of movement and the concentration of the alcohol distributed into the lipid phase of a lipid-water mixture. The ratio of the concentration in the lipid phase to the concentration in the aqueous phase at equilibrium is known as the Overton-Meyer or lipid-water partition coefficient. The higher the partition coefficient, the less alcohol was needed to cause cessation of movement. 

In the early 1900s Hans Meyer and Charles Overton suggested that the potenoy of a substanoe as an anesthetic was directly related to its lipid solubility, or oil/gas partition ooeffioient (4,5). This has oommonly been referred... 

The discovery of a parameter (olive oil/water partition coefficient) upon which a mechanistic interpretation for narcosis could be based was made independently six years later by Charles Ernest Overton at the University of Zurich (30-31) and by Hans Horst Meyer (32) and his collaborator Fritz Baum (33) at the University of Marburg. Prior to this discovery, Walter Dunzelt, a student of Meyer, attempted to confirm the Houdaille data on the relationship between water solubility and minimum toxic concentration, using tadpoles and small fish (34). 

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