Mexate - Methotrexate

Methotrexate is used to treat severe lymphatic leukemia, choriocarcinoma, non-Hodgkin s lymphoma, bone carcinoma, as well as head, neck, breast, and lung tumors. Synonyms of this drug are farmitrexate, ledertrexate, ematexate, maxtrex, folex, mexate, and others. 

Proprietary Names of Methotrexate and Methotrexate Sodium. Emtexate Ledertrexate Mexate. 

Methotrexate (e.g., Mexate) Inhibits dihydrofolate reductase, an enzyme that catalyzes the synthesis of thymidine. DNA synthesis is thus impaired. Prevention of organ transplant rejection, severe psoriasis. Bone marrow depression, Gl ulceration, nephrotoxicity, hepatotoxicity, pulmonary infiltration, skin toxicity. 

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