Metronidazol lotion

Metronidazole lotion contains metronidazole USP at a concentration of 7.5 mg per gram (0.75% w/w) in a lotion consisting of benzyl alcohol, carbomer 941, cyclomethi-cone, glycerin, glyceryl stearate, light mineral oil, PEG-100 stearate, polyethylene glycol 400, potassium sorbate,... 

Sulfacetamide 10%/sulfur 5% cream or lotion once a day (in certain patients might be less irritating than metronidazole) [5]... 

Topical preparations for the treatment of rosacea include metronidazole 0.75% or 1% cream, 0.75% gel, or lotion. None of these preparations is FDA-approved for ophthalmic use, but they have been beneficial fiar some patients. 

Sanchez J, Somolinos AL, Almoddvar PI, Webster G, Bradshaw M, Powala C (2005) A randomized, double-blind, placebo-controUed trial of the combined effect of doxycy-cline hyclate 20-mg tablets and metronidazole 0.75% topical lotion in the treatment of rosacea, J Am Acad Dermatol 53 791-797... 

Miconazole was originally marketed only for topical use in a 2% cream, lotion and powder. Allergic contact dermatitis to miconazole has recently been described. De Greef et al. (16 ) noted aggravation in 8 of 108 patients treated with the 2% cream, of whom one had a positive patch test to 2% miconazole. Van Ketel(17 -) described patch tests in one patient with a clinical reaction to the cream after 6 weeks use, with a positive patch test to 2% miconazole in vaseline and negative tests to the related imidazole derivatives mebendazole, tinidazole and metronidazole. 

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