Methylamines physiological effects

These studies of protein structure, like those of urea and methylamine effects on enzyme kinetic parameters, reveal that physiological mixtures of counteracting solutes achieve essentially the same end result as use of compatible solutes regulating cell volume through adjusting concentrations of compatible solutes or counteracting solutes (at the appropriate ratio of concentrations) conserves critical aspects of protein structure and function as well as cell volume per se. 

Davidson, V. L., Graichen, M. E., and Jones, L. H., 1993, Binding constants for a physiologic electron-transfer protein complex between methylamine dehydrogenase and amicyanin. Effects of ionic strength and bound copper on binding, Biochim. Biophys. Acta 1144 3 9n 45. 

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