Methyl-3,4,5,6-tetrabromophenol

Remarkably compatible with skin, mucosa and eyes. 

The compound is very effective against Staphylococci (MIC approx. 2.5mg/litre), but very much less active against Pseudomonads (MIC 2000 mg/litre). Remarkable is the efficacy of tetrabromo-o-cresol against algae (MIC for Chlorella species 1 mg/litre). 

It has been proposed to use the compound as a preservative for cosmetics or as an active ingredient in deodorants or for the antimycotic treatment of textiles. However, the significance of tetrabromo-o-cresol has remained very limited (probably due to poor water-solubility, coloration risks and costs). 

Microbicide group (substance class) Chemical name Chemical formula Structural formula 

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Tetrabromocresol 3,4,5,6-Tetrabromo-o-cresol. See Tetrabromo-o-cresol Tetrabromo-o-cresol CAS 576-55-6 EINECS/ELINCS 209-403-8 Synonyms 2-Methyl-3,4,5,6-tetrabromophenol 3,4,5,6-Tetrabromocresol 3,4,5,6-Tetrabromo-o-cresol... 

Methyl-4-nitro-2,3,5,6-tetrabromocyclohexa-2,5-dienone, a regiospecific nitrating agent was obtained in 88% yieid by the addition at 100°C over 10 mins, of nitric acid (d 1.52) to 4-methyl-2,3,5,6-tetrabromophenol in acetic acid followed by reaction for 2 hours at 5 C (ref.28). 

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