4- Methyl-2-pentanone, reaction with

Allylcyciohexanone, 42,14 Allyllithium, 41, 30 from allyltin derivatives, 41, 32 reaction with 4-methyl-2-pentanone, 41,30... 

The activated Ba(OH)2 catalyst was successfully used for the Michael reactions of chalcone with active methylene compounds 290), as well as for the Michael reaction of other benzylidene derivatives of acetone, butanone, 3-methylbutanone, 4-methyl-2-pentanone, and 3,3-dimethylbutanone with ethyl acetoacetate and diethyl malonate. The reaction with diethyl malonate gave good yields of the Michael adduct (between 65 and 93%), whereas with ethyl acetoacetate various products were obtained, depending on temperature and amount of catalyst (Scheme 43) 291). Thus, by varying the reaction conditions, it was possible to obtain a single product with practically 100% selectivity, the yields being higher than those obtained with soluble catalysts, such as KOH, NaOH, or piperidine. 

Tetramethyl-3-piperideine (35) may be prepared from mesityl oxide via diacetoneamine (4-amino-4-methyl-2-pentanone) and reaction with acetaldehyde to give 2,2,6-trimethyl-4-piperidone, which is then treated with methylmagnesium iodide and dehydrated.28... 

Access to key materials for synthesis in this group has been possible for some years by reaction of acrolein with 2-methyl-3-pentanone in presence of p-toluenesulfonic acid, distilling off the water formed during the reaction, and leading to 2,6,6-trimethyl-2-cyclohexenone (690). Alternatively, 2-methyl-3-pentanone reacts with methyl acrylate in the presence of base (sodium methoxide/ methanol in xylene) to give 92% of the diketone 691 (probably as the enol). ... 

These cyclization reactions were also possible with or without a metal ion template using a,j3-unsaturated ketones, such as mesityl oxide or methyl vinyl ketone, or with /3-hydroxyketones, such as 4-hydroxy-4-methyl-2-pentanone. The products were the same as when simple carbonyl compounds were used showing that the reaction with the simple carbonyl compounds proceded... 

The solvent effect in Mn2(CO)io polymerizations was explored with over 40 solvents [51] and perfluorobutyl iodide (PFBI), easily activated by Mn(CO)5 (vide infra) was used as initiator. The comparisons were made under the same conditions (VDF/PFBI/Mn2(CO)io = 25/1/0.2 VDF/solvent = 1/3 wt/v) and revealed that in accordance with the principles outlined above, no polymerization occurred in anisole, a,a,a-trifluorotoluene, diglyme, diethylene glycol monoethyl ether, ethyl ether, THF, dioxane, o-cresol, isopropanol, trifluoroacetic anhydride, tetramethylurea, sulfolane, benzonitrile, cyclopentanone even after 1-3 days. Poor reaction rates (/ p PP < 1 - 9 X 10 h ) were observed in HMPA, 2-butanone, methyl pentanone, DMF, DMSO, PEO, DMAc, 5-valerolactone, BuOH, and EtOAc. Slightly faster polymerizations (/ p PP = 1 - 1.7 X 10 h ) were seen in CH2CI2, acetic anhydride, y-butyrolactone, 1,2-dichloroethane, TMP, MeOH, pentafluorobutane, and HFBz,... 

A derivative of 11-azaequilenin (458) has been obtained from 1-amino-6-m ethoxy naphthalene (456) by its reaction with qj-ethoxy carbonylcyclo-pentanone and subsequent cyclization and reduction of the tricyclic diketone (457) (Scheme 44). The nature of the linkage of rings C and D in the reaction product (458) has not been established. An attempt to extend these reactions to the analog of (458) with an angular methyl group was unsuccessful [557]. ... 

SCHEME 1.72 Reaction of 2-hydroxy-2-methyl-4-pentanone oxime with acetylene in KOH/DMSO system. 

Used as 0.01% soln. in EtOAc to give colour reactions with Ag, Bi, Cd, Co, Cu, Pb. Yellow cryst. Sol. MeOH, CHCI3, EtOAc, 4-methyl-2-pentanone. Mp 212°. 

Combining fc(OH 2-methyl-2-pentanol) = 7.1 x 10 cm molecule s with a diurnal average [OH] = 10 molecule cm provides an estimate of approximately 2 days for the atmospheric lifetime of 2-methyl-2-pentanol with respect to reaction with OH. Bethel et al. (2003) studied the products of the OH-initiated oxidation of 2-methyl-2-pentanol in the presence of NO using GC-FID, GC-MS and API-MS analytical techniques. The identified products were acetaldehyde (22 3%), propanal (35 4%), acetone (56 6%), and 2-pentanone (5 1%). The sum of the hydroxynitrate and dihydroxynitrate yields was 8%. Acetone is a co-product of both acetaldehyde and... 

The atmospheric lifetime of 2,4-dimethyl-2-pentanol with respect to reaction with OH radicals is estimated to be 10 h using [OH] = 2.5 x 10 molecule cm and the rate coefficient presented in this section. The product study conducted by Atkinson and Aschmann (1995) using GC-FK) and GC-MS showed that the reaction of OH with 2,4-dimethyl-2-pentanol gives the following products (molar yields) Acetone (92 15%), 2-methylpropanal (21 22%), 4-methyl-2-pentanone (5 1%), and 4-hydroxy-4-methyl-2-pentanone (12 2%). In addition, the yield of a tertiary nitrate was estimated to be 4 1%. 

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