4-Nitro-2-methyl-1-pyrrolidino

Carboxyl group of (-)-9-fluoro-3-methyl-7-oxo-10-[(3S)-3-(tert-butoxy-carbonylamino)pyrrolidino]-2,3-dihydro-7//-pyrido[l,2,3- 7e]-l,4-benzoxa-zine-6-carboxylic acid was converted into l-nitro-2-oxoethyl group in 45% yield by treatment with l,l -carbonyldiimidazole in boiling CFICI3 for 18h, then with MeN02 in the presence of KOr-Bu for another 18 h (96MI12). 6-(2,2-Diethoxycarbonyl)acetyl derivative formed from the aforementioned 6-carboxylic acid, when it was treated with l,l -carbonyldiimidazole in... 

Nitromethyl-l-oxo-cycloalkane bzw. 1-Nitromethyl-cycloalkene lassen sich mit Pyrro-lidinen oder (S,)-2-Methoxymethyl-pyrrolidin bzw. -piperidin in Acetonitril bei 20° unter Austausch der Nitro-Gruppe in guten Ausbeuten in 2-(Pyrrolidino-methyl)-l-oxo-cycloalkane3 bzw. l-(Piperidino-methyl)-cycloalkene8 uberfuhren (s.a. S. 378) ... 

Some fragmentation pathways of 4(5)-piperidino-, 4(5)-pyrrolidino- and 4(5)-morpholinosubstituted 5(4)-nitro-2-methylimidazoles [1303], and l-organyl-2-methyl-4-nitroimidazoles and their 5-iodo derivatives have been studied [1304],... 

Pyrrolidinocyclohexene added drop wise at 0° under Ng (maintained throughout the reaction) during a few min. to a soln. of 2-nitro-l-phenylpropene in dry hexane, then allowed to warm to troom temp., and the product isolated after 2 hrs. -> 3-methyl-4-phenyl-8a-pyrrolidino-4a, 5,6,7,8,8a-hexahydro-4H-l, 2-benz-oxazine 2-oxide. Y 91%. F. e. s. A. T. Nielsen and T. G. Archibald, Tetrahedron 26, 3475 (1970). 

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