5- Methyl-l,10-phenanthroline

Fe(5-methyl-l,10-phenanthroline) +eC H2SO4 Fe(5 -phenyl-1,10-phenanthroline) —> 1.08 52Bra... 

Methyl-l,10-phenanthroline [3002-78-6] M 194.2, m 113 (anhydr). Crystd from benzene/pet ether. 

Not many reduction potentials are known for copper complexes. That of the Cu2+/Cu+ couple is 0.16 V Since lo(Cu+/Cu°) is 0.52 V, the disproportionation of Cu+ to Cu° and Cu2+ is favourable. This reaction does indeed occur, which makes is impossible to study stable copper(I) solutions. Reduction potentials of copper(II)-/copper(I)-(l,10-phenanthroline)2 and a few derivatives have been calculated from a kinetic analysis of appropriate rate constants values range from 108 mV for the 5-methyl-l, 10-phenanthroline complex to 219 mV for the complex with a nitro group at the 5 position [52], Values of 0.17 V and 0.12 V are given by Phillips and Williams [53] for the phenanthroline and bipyridine complexes, respectively. Such complexes can thermodynamically catalyse both the superoxide dismutation and the one-electron reduction of hydrogen peroxide (see below). 

Methyl-l,10-phenanthroline [3002-78-6] M 194.2, m 67 (monohydrate), 113 (anhydrous), pK 5.28. Crystallise it from berrzene/petroleum ether or from H2O as the monohydrate. It complexes with many metals. [Beilstein 23III/IV 1714.]... 

Inhibition of bovine CA by 5-methyl-l,10-phenanthroline and aniline involves direct tertiary co-ordination to the zinc ion. With the latter reagent, however, H n.m.r. relaxation of metal-bound water is unchanged on aniline co-ordination suggesting either that a histidine ligand is replaced or that a fifth co-ordination site is available. By contrast, methanol binds at a hydrophobic region ca. 6 A from the metal site and shows non-competitive inhibition of p-nitrophenyl acetate hydrolysis activity. ... 

The addition of potassium, caesium, or tetra-alkylammonium (alkyl = methyl, ethyl, or n-butyl) salts has a marked effect on the rate of aquation of the tris-(5-nitro-l,10-phenanthroline)iron(n) cation. For a given concentration of added salt,... 

Ligand abbreviations phen = 1,10-phenanthroline bpy = 2,2 -bipyridine phy = l,10-phenanthroline-2-carhaldehyde phenylhydra-zone 2-pic = 2-aminomethylpyridine bt = 2,2 -bi-2-thiazoline bts = 2,2 -bi(5-methyl-2-thiazoline) H fsajen = JV,JV -ethylenebis (3-carboxysalicylaldimine)... 

The phenolic functions are deprotected under rather drastic conditions, by analogy with methods defined previously for the cleavage of aryl methyl ethers.14 Treatment of dianisylphenanthroline 4 with pyridinium hydrochloride at 210°C affords 2,9-di(p-phenol)-l,10-phenanthroline 5 quantitatively (Scheme 9.4). 

The divalent metal ion complexes of 2,2 -dipyridyl and 1,10-phenan-throline derivatives are much more susceptible to pseudobase formation than the corresponding N-alkyl quaternary cations. Thus, pXR+ > 14 for pseudobase formation by the N-methyl monocations of both 2,2 -dipyridyl and 1,10-phenanthroline,46 whereas the Pt2+ complexes of these heterocycles have pKR, values of 9.0 and — 11.5, respectively.361,369 This latter value indicates that Pt(l,10-phenanthroline)i+ is less susceptible to pseudobase formation than the 1,10-phenanthrolinium dications 17 (pKR+ = 9.54) and 18 (pKR+ = 9.17).46... 

MePTZ = lO-methylphenothiazine 2,3-dpp = 2,3-bis (2-pyridyl)pyrazine 2,9-Me2-4,7-Ph2-phen = 2,9-dimethyl-4,7-diphenyl-l,10-phenanthrolme 2,9-Me2-phen = 2,9-dimethyl-1,10-phenanthroline 3,4,7,8-Me4-phen = 3,4,7,8-tet-ramethy 1-1,10-phenanthroline 4,4 - NH2 2-bpy = 4,4 -dia-mino-2,2 -bipyridine 4,4 -Me2-bpy = 4,4 -dimethyl-2,2 -bipyridine 4, 4 -Ph2-bpy = 4,4 -diphenyl-2,2 -bipyridine 4, 4 - Bu2-bpy = 4,4 -di-tert-butyl-2,2 -bipyridine 4,7-Me2-phen = 4,7-dimethyl-l,10-phenanthroline 4-MeOPh-HPh bpy = 4 -(4-methoxyphenyl)-6 -phenyl-2,2 -bipyridine 4-Me-phen = 4-methyl-1,10-phenanthroline 5,6-Me2-phen = 5,6-dimethyl-l,10-phenanthroline 5-Ph-phen = 5-phenyl-1,10-phenanthroline bimy = benzimidazol-2-ylidene biq = 2,2 -biquinoline bpy = 2,2 -bipyridine bpy-dvb-bpy = 1,4-bis[2-(4 -methyl-2,2 -bipyrid-4-yl)ethenyl]benzene bpy-pyrl = 4-(2-pyrrol-l-ylethyl)-4 -methyl-2,2 -bipyridine bpy-pyr2 = 4,4 -bis((3-pyrrol-l-ylpropyloxy)carbonyl)-2,2 -bipyridine BSA = bovine serum albumin BTA = bis(trimethylsilyl)acetylene chrysi = 5,6-chrysenequinone diimine COD = 1,5-cyclooctadiene DAB = 1,4-diaza-1,3-butadiene DFT = density functional theory dmb =1,8-diisocyano-/ -menthane dmb-tol = 4-methyl-4 -(iV-methyl-/ -tolylaminomethyl)-2,2 -bipyridine dmpe = l,2-bis(di-methylphosphino)ethane dmpm = bis(dimethylphosphino) methane dpmp = bis(diphenylphosphinomethyl)phenylphos-phine dppb = l,2-bis(diphenylphosphino)benzene dppe = l,2-bis(diphenylphosphino)ethane dpp-HCNN = 2,9-di-... 

Recently, we reported a terbium complex Tb(PMIP)3(PhCN) (Tb-29, PMIP= 1-phenyl-3-methyl-4-isobutyl-5-pyrazolone PhCN = pyrazino[2,3-/][l,10] phenanthroline-2,3-dicarbonitrile, Figure 13.13) as a reagent for anions [50]. Interestingly, the luminescent... 

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