3- methoxycarbonylphenyl methyl

Although the preparation has been repeated, there have been no other reports of the type of reaction, (described in 1923) in which carbazole in the presence of excess potassium hydroxide and nitrobenzene at only 50°C gave a good yield of 9-(4-nitrophenyl)-carbazole, presumably via an adduct such as 43 subsequently oxidized by excess nitrobenzene and/or air. More recent examples of N-arylation of carbazoles have involved copper catalysis in reaction of aryl halides with carbazoles. Thus, copper bronze and potassium carbonate heated with the carbazole and the appropriate aromatic halide have produced 9-(4-methoxyphenyl)- and 9-(2-tolyl)carbazoles 9-(4-phenylphenyl)carbazole, l,4-di(carbazol-9-yl)benzene, 4,4 -di(carbazol-9-yl)biphenyl, and 9-(2-pyridyl)- and 9-(2-quinolyl)carbazoles 9-[2-(2-phenylphenyl)phenyl]- and 9-[2-(4-methylphenyl)phenyl] carbazoles 9-(3-bromo-6-nitrophenyl)-, 9-[3-(carbazol-9-yl]-, 9-(2-nitrophenyl)-, 9-(4-methyl-2-nitrophenyl)-, 9-(4-methoxycarbonyl)-l-nitro-, and l-nitro-9-(4-tolyl)carbazoles 9-(2-methoxycarbonylphenyl)carbazole 9-[2- 2-... 

N-(3-chloro-5-methoxycarbonylphenyl)-5-bromo-l,2,3,4-tetrahydro-quinoline-8-carboxamide was obtained from 8-bromo-6,7-dihydro-lH,3H,5H-pyrido[3,2,l-z/][3,l]benzoxazine-l,3-dione with methyl 3-amino-5-chlorobenzoate in NMP at 170 °C for 16 h (07WOP2007/028789). 

In order to determine whether a bridge containing at least two atoms is necessary for antifolate activity, Nair et al. [139] prepared V-[4-(2,4-diamino-6-pteridinyl)methyl]benzoyl-L-glutamate ( 9-nor-lO-deaza-AMT (IV. 160)). 1-Bromo-3-(4-methoxycarbonylphenyl)-2-propanone was converted by a series of standard reactions to the azido ketal acid (IV. 161), which was condensed with diethyl L-glutamate by the mixed anhydride method to form the diester (IV. 162). Reduction of the azido group followed by reaction with 2,4-diamino-... 

To a mixture of 2-methoxycarbonylphenyl tosylate (293, 3.04 g, 10 irnnol), phenyl boronie acid (260, 1.83 g, 15 mmol,1.5 eq.) and potassium phosphate (4.25 g, 20 mmol, 2 eq.) in dioxane (20 ml), deggased with argon was added Ni(PCy3)2Cl2 (210 mg, 0.3 mmol, 3 mol%) followed by tricyclohexylphosphine (340 mg, 0.12 mmol, 4 eq. to Ni). The reaction mixture was refluxed under argon for 60 h. Then the solvent was evaporated and the residue was chromatographed on silica gel column (n-hexane / dichloromethane) affording 1.0 g (47%) of pure methyl biphenyl-2-carboxylate (294). 

Poly(l-phenylethylene) Polystyrene -[C HgCHCHJ Poly[l-(4-acetylphenyl)ethylene] Poly[l-(4-benzoylphenyl)ethylene] Poly[l-(4-bromophenyl)ethylene] Poly[l-(4-butoxyphenyl)ethylene] Poly[l-(4-butoxycarbonylphenyl)ethylene] Pol[(l-(4-butylphenyl)ethylene] Poly[l-(4-carboxyphenyl)ethylene] Poly[l-(2-chlorophenyl)ethylene] Poly[l-(3-chlorophenyl)ethylene] Poly[l-(4-chlorophenyl)ethylene] Poly[l-(2,4-dichlorophenyl)ethylene] Poly[l-(2,5-dichlorophenyl)ethylene] Poly[l-(2,6-dichlorophenyl)ethylene] Poly[l-(3,4-dichlorophenyl)ethylene] Poly[l-(2,4-dimethylphenyl)ethylene] Poly[l-(4-(dimethylamino)phenyl)ethylene] Poly[l-(4-ethoxyphenyl)ethylene] Poly[l-(4-ethoxycarbonylphenyl)ethylene] Poly[l-(4-fluorophenyl)ethylene] Poly[l-(4-iodophenyl)ethylene] Poly[l-(4-methoxyphenyl)ethylene] Poly[l-(4-methoxycarbonylphenyl)ethylene] Poly(l-methyl-l-phenylethylene)... 

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