1-methoxy-1-phenyl

The methoxy group is replaced in the reaction of 3-methoxy-5-phenyl-1,2,4-triazine 1-oxide 46 with ammonia, resulting in 3-amino-5-phenyl-1,2,4-triazine 1-oxide 47. The treatment of 3-methoxy-1,2,4-triazine 1-oxide 20 with hydrazine leads to 3-hydrazino-1,2,4-triazine 1-oxide 48 (71JOC787). 

The 3-methoxy-5-phenyl isomer (114) was synthesized from the thio compound59 197 (113), which was hydrolyzed to 115 by pyridine hydrochloride. Diazomethane, acting on 3-hydroxy-5-phenyloxadiazole (115)... 

Methoxy-l-phenyl-2(l//)-pyrazinone 3-Methoxy-5-phenyl-2(l//)-pyrazinone 5-Methoxy-3-phenyl-2(l//)-pyrazinone 5-Methoxy-6-phenyl-2(l/7)-pyrazinone 2- Methoxy-3 -propionylpyrazine... 

Methyl-3-methoxy-5-phenyl-hexa-3,4-diene (114) Carbon chemical shift 370, 372. 

Benzaldehyde in tetrahydrofuran containing a little coned. HCl added by syringe under Ng to a soln. of l-methyl-2-phenyl-4-methoxypyrrole in the same solvent, and the product isolated after 15 min. l,l,2-tris-(l-methyl-3-methoxy-5-phenyl-2-pyrryl)-l,2-diphenylethane. Y 77%. - The above startg. pyrrole is unusually reactive. E. Campaigne and G. M. Shutske, J. Heterocyclic Chem. 12, 1047 (1975). 

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