6 -Methoxy-2 -acetonaphthone

Bromo-6 -methoxy-2 -acetonaphthone and 2,2-dibromo-6 -methoxy-2 -acetonaphthone)... 

Electrochemistry offers new routes to the production of several commercially relevant a-arylpropionic acids, used as non-steroidal anti-inflammatory agents (NSAI) [178,182]. A preparative method based on sacrificial Al-electrodes has been set up for the electrocarboxylation of ketones [117,183-187] and successfully applied to the electrocarboxylation of aldehydes, which failed with conventional systems. The electrocarboxylation of 6-methoxy-acetonaphthone to 2-hydroxy-2-(6-methoxynaphthyl)propionic acid, followed by chemical hydrogenation to 2-(6-methoxynaphthyl)-2-propionic acid - one of the most active NSAI acids - has been developed up to the pilot stage [184,186],... 

The remaining compounds possess it,it emitting triplets in all media used (Group III). The members of this class are 1,2-diphenylacetone, o-methoxy-acetophenone, xanthone, and 2 -acetonaphthone. This group is characterized by a long-lived phosphorescence in all solvents and by a decrease in the energy of the emitting triplet upon increased solvent polarity. 

Methyl 3-methoxy-596 7,8-tetrahydro-2-naphthoate—To 300 ml of potassium hypochlorite solution [12] (ca. 0 46 mole of hypochlorite) at 11° was added, with stirring, 2 0 g (0 0098 mole) of 3-methoxy-5,6,7,8-tetrahydro- 2 acetonaphthone in 60 ml of methanol. The mixture was stirred for 5 hours at 11-30°. Filtration separated 0 92 g of yellow... 

The ruthenium-catalyzed addition of C-H bonds in aromatic ketones to olefins can be applied to a variety of ketones, for example acetophenones, naphthyl ketones, and heteroaromatic ketones. Representative examples are shown in the Table 1. Terminal olefins such as vinylsilanes, allylsilanes, styrenes, tert-butylethy-lene, and 1-hexene are applicable to this C-H/olefin coupling reaction. Some internal olefins, for example cyclopentene and norbornene are effective in this alkylation. The reaction of 2-acetonaphthone 1 provides the 1-alkylation product 2 selectively. Alkylations of heteroaromatic ketones such as acyl thiophenes 3, acyl furans, and acyl pyrroles proceed with high yields. In the reaction of di- and tri-substitued aromatic ketones such as 4, which have two different ortho positions, C-C bond formation occurs at the less congested ortho position. Interestingly, in the reaction of m-methoxy- and m-fluoroacetophenones C-C bond formation occurs at the congested ortho position (2 -position). 

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