Method of temperature jump

Nondegenerate double proton migrations between a solute molecule and the molecules of the solvent (water) may determine the mechanism of intermolecular proton transfers that give rise to a new tautomeric form. Thus, using the relaxation method of temperature jump, it was found [97] that the tauto-merization of 6-methoxy-2-pyridone proceeds as a nondissociative concerted process of bifunctional interaction with one molecule of water ... 

Moreover, since this interexchange is very slow, the kinetics of interconversion of active dormant could be directly observed by using NMR. The method of temperature jump was applied from an equilibrium state (cf. Scheme 12) at one temperature, kinetics of attaining an equilibrium at another temperature could be measured since the time needed for changing temperature in the NMR tube was much shorter than the time for reaching a new equilibrium (see Scheme 12, where fetd is the rate constant of temporary deactivation and feio is the rate constant of back activation (ionization)). The actual set of the NMR spectra at various stages of interconversion is... 

Due to the mutual attraction when r ff > r/, the recombination of unlikely chaiged ions occurs very promptly, more promptly than radical recombination. This is seen from the data presented below and obtained by the method of temperature jump... 

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