Methanol arsine oxides

Jakubowski et al. (36) developed a GC/MS method for CVAA spiked into guinea pig urine using 1,2-ethanedithiol for derivatization, with phenyl arsine oxide as the internal standard. The same group later expanded the method to include atomic emission detection (AED) (37). CVAA was concentrated from urine (adjusted to pH 6 with 1M HC1) by SPE on Cl8. After elution with methanol and concentration to dryness, the residue was reconstituted and derivatized with ethanolic 1,2-ethanedithiol. Detection was by GC combined with arsenic selective AED and by electron impact/mass spectrometry (EI/MS) using SIM. Ions monitored were the moderately intense M+ ion at mlz 228, an intense ion [M — C2H4]+, mlz 200, and a base... 

Bulk aluminum may undergo the following dangerous interactions exothermic reaction with butanol, methanol, 2-propanol, or other alcohols, sodium hydroxide to release explosive hydrogen gas. Reaction with diborane forms pyrophoric product. Ignition on contact with niobium oxide + sulfur. Explosive reaction with molten metal oxides, oxosalts (nitrates, sulfates), sulfides, and sodium carbonate. Reaction with arsenic trioxide + sodium arsenate + sodium hydroxide produces the toxic arsine gas. Violent reaction with chlorine trifluoride, Incandescent reaction with formic acid. Potentially violent alloy formation with palladium, platinum at mp of Al, 600°C. Vigorous dissolution reaction in... 

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