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Methacycline

Fig. 1. Tetracycline (1) and its derivatives chlortetracycline (7-chlorotetracycline) (2) oxytetracycline (5-hydroxytetracycline) (3), demeclocycline (6-demethyl-7-chlorotetracycline) (4) methacycline (6-demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline) (5) doxycycline (6a-deoxy-5-hydroxytetracycline) (6) and minocycline (6-demethy1-6-deoxy-7-dimethy1 amino tetracycline) (7). Substituents at positions not specifically... Fig. 1. Tetracycline (1) and its derivatives chlortetracycline (7-chlorotetracycline) (2) oxytetracycline (5-hydroxytetracycline) (3), demeclocycline (6-demethyl-7-chlorotetracycline) (4) methacycline (6-demethyl-6-deoxy-5-hydroxy-6-methylenetetracycline) (5) doxycycline (6a-deoxy-5-hydroxytetracycline) (6) and minocycline (6-demethy1-6-deoxy-7-dimethy1 amino tetracycline) (7). Substituents at positions not specifically...
Hydrogen was introduced into a standard hydrogenation vessel containing 10 grams 6-deoxy-6-demethyl-6-methylene-5-oxytetracycline hydrochloride (methacycline), 150 ml methanol and 5 grams 5% rhodium on carbon. The pressure was maintained at 50 psi while agitating at room temperature for 24 hours. The catalyst was then filtered off, the cake washed with methanol and the combined filtrates were evaporated to dryness. The dry solids were slurried in ether, filtered and the cake dried. The resulting solids exhibited a bioactivity of 1,345 units per mg versus K. pneumoniae. [Pg.542]

Tabalgin - Acetaminophen Tabrien Feprezone Tacaryl Methdilazine HCI TACE Chlorotrianisene Tacef Cefmenoxime TACE FN - Chlorotrianisene Tachiciclina - Methacycline Tachionin Trichlormethiazide Tachipirina Acetaminophen... [Pg.1745]

Visumicina Bekanamycin sulfate Visumidriatic - Tropicamide Visutensil Guanethidine sulfate Vitabiotic Methacycline Vitae Chlorpheniramine maleate Vitacarotene - /3-Carotene Vitacid-A Tretinoin Vitacontact Chlorhexidine Vitacort Prednisolone Vitafol Folic acid Vita-K Phytonadione Vitaklorin- Chloramphenicol Vitamin-A-Saure Tretinoin Vitamine K1 Phytonadione Vitarubin Cyanocobalamin Vi-Twel Cyanocobaiamin Vivactil Protriptyline Vival - Diazepam Vivalan Viloxazine HCI... [Pg.1755]

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Hormonal) Methacycline

Methacycline Doxycycline

Methacycline hydrochloride

Rondomycin - Methacycline

Tachiciclina - Methacycline

Vitabiotic - Methacycline

Yatrociclina - Methacycline

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