Metal-mediated peptide assembly

Metal-Mediated Peptide Assembly From Diserete Moleeular Speeies to Large-Seale Morphologies... 

In an novel approach, a metal ion mediated self-assembly process [6] is used in the spirit of the new inclusive definition of coordination chemistry. Peptides or amino acids can be covalently linked to a metal-binding ligand. 

Nanostmcture science and supramolecular chemistry are fast evolving fields that are concerned with manipulation of materials that have important structural features of nanometer size (1 run to 1 pm) [10, 11]. Nature has been exploiting no covalent interactions for the construction of various cell components. For instance, microtubules, ribosomes, mitochondria, and chromosomes use mostly hydrogen bonding in conjunction with covalently formed peptide bonds to form specific stmctures. The self-assembled systems and self-organized stmctures mediated by transition metals are considered in coimection with increasing research interest in chemical transformations with use of these systems [12]. 

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