Metagenomic mining

The recently developed methodology for enzyme discovery that is based on random DNA isolation and subsequent screening (metagenome mining) is... 

Owen, J.G., Charlop-Powers, Z., Smith, A.G., Ternei, M.A. et al. (2015) Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors. Proc. Natl. Acad. Sci. U.S.A., 112 (14), 4221-4226. 

As briefly mentioned above, the accumulated knowledge and the discoveries connected with genome mining and accessing the metagenome of soil-borne... 

Ferrer M, Martinez-Abarca F, Golyshin PN (2005) Mining gtaiomes and metagenomes for novel catalysts. Curr Opin Biotechnol 16 588-593... 

Veronese G (2010) Functional metagenomics to mine the human gut microbiome for dietary fiber catabolic enzymes. Genome Res 20( 11) 1605—1612 Taylor M, Marmer W, Brown E (2007) Evaluation of polymers prepared from gelatin and casein or whey as potential fillers. J Am Leather Chem Assoc 102(4) 111-120... 

Taherzadeh, M.J., Karimi, K., 2007. Enzymatic-based hydrolysis processes for ethanol. BioResources 2 (4), 707-738. Tasse, L., Bercovici, J., Pizzut-Serin, S., Robe, R, Tap, J., Klopp, C., Cantarel, B.L., et al., 2010. Fvmctional metagenomics to mine the human gut microbiome for dietary fiber catabolic enzymes. Genome Research 20 (11), 1605-1612. Van Berkel, R., 2000. Cleaner Rroduction for Rrocess Industries. Plenary Lecture. Chemeca, Perth WA. 

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