Metagenome technology

Recent advances in recombinant DNA technology, high-throughput technologies, genomics and proteomics, have fuelled the development of new biocatalysts and biocatalytic processes. In particular, site directed mutagenesis, directed evolution or metagenome approach are very valuable tools to enhance lipase properties. 

Metagenomics, personalized medicine, and future bioinformatics initiatives yet to be discovered will rapidly affect nearly all individuals. It is not surprising that with these major advances in bioinformatics technologies comes a caution by many for careful introspection and debate of their implications. Interest in bioethics is on the rise and has been added to the curricula of not only bioinformatics educational programs but those of many other disciplines as well. 

Despite advances in modem technology and increased understanding of both human and microbial genomes, a number of important questions remain. Large-scale microbiome-characterization efforts such as the Human Microbiome Project and American Gut, coupled with advances in both metagenomics and metabolomics are starting to reveal the importance and complex interactions of the gut microbiota. Both prebiotic... 

Metatranscriptomics, metaproteomics, and metabolomics are also widely used in conjunction with metagenomic analyses. These omic technologies can provide a more comprehensive understanding of the types of genes being expressed... 

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