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Metabolism 17/3-hydroxyl group protection, effect

Figure 29 Protected ManNAc analogs with C-1 or C-6 free hydroxyls (R = acetyl or butyryl groups). A free hydroxyl at the C-1 position has little effect on metabolic flux but negatively impacts cell viability. A free hydroxyl at the C-6 position improves metabolic flux and increases cell viability. Figure 29 Protected ManNAc analogs with C-1 or C-6 free hydroxyls (R = acetyl or butyryl groups). A free hydroxyl at the C-1 position has little effect on metabolic flux but negatively impacts cell viability. A free hydroxyl at the C-6 position improves metabolic flux and increases cell viability.
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1,2-hydroxyl groups, protecting group

Hydroxyl group, protection

Hydroxyl-protecting groups

Hydroxylation metabolic

Hydroxylation metabolism

Metabolic effects

Metabolic protection

Metabolism effects

Protecting-group effect

Protection effects

Protective effects

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