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1,2-hydroxyl groups, protecting group

Reduction with (/-Bu)2AlH affords a diol, with one hydroxyl group protected as a MOM group. The more substituted hydroxyl bears the MOM group. ... [Pg.231]

In a prostaglandin synthesis, a carbonyl group was protected as an oxime that had its hydroxyl group protected against Collins oxidation by the phenyl-thiomethyl group. The phenylthiomethyl group is readily removed to give an oxime that is then cleaved to the carbonyl compound. ... [Pg.359]

Hydroxyl groups protected as acetonides or as silyl, tetrahydropyranyl, benzyl, or methoxymethyl ethers are stable to these conditions. Yields with KMn04 are higher than those obtained with KMn04 and dicyclohexyl- 18-crown-6, Bu4NMn04, or NaMn04H20. ... [Pg.267]

Aldonolactones having their hydroxyl groups protected as ethers (mainly benzylated and silylated derivatives) have been employed for chain elongation through the carbonyl group, and therefore these type of derivatives are included in Section V. [Pg.133]

The chiral cyanohydrins also lead directly to a-hydroxy acids by hydrolysis (sequence B) [69] and to protected a-hydroxy aldehydes by first hydroxyl group protection, followed by reduction of the nitrile and hydrolysis of the intermediate imine (not shown) (sequence C) [114]... [Pg.51]

Ethyl vinyl ether is also useful for hydroxyl-group protection. The resulting derivative (1-ethoxyethyl ether) is abbreviated as the EE group.5 As with the THP group, the EE group contains a stereogenic center. [Pg.823]

Hydroxyl group, protection of, 10-142 as esters, 87-118 Reactivity Chart 2, 417-420 as ethers, 14-87 ... [Pg.238]

The benzyloxycarbonyl group (Cbz or Z) is useful in carbohydrate syuithesis, not only for IV-protection of amino sugars, but also to protect alcohols [262,263]. The main advantage of this group is that it is cleaved by hydrogenolysis, and when compared to benzyl ethers, benzyl carbonates are not only removed more readily [264] but also allow hydroxyl group protection under softer conditions than those employed for benzylation. [Pg.138]


See other pages where 1,2-hydroxyl groups, protecting group is mentioned: [Pg.82]    [Pg.244]    [Pg.401]    [Pg.638]    [Pg.3]    [Pg.72]    [Pg.96]    [Pg.224]    [Pg.782]    [Pg.70]    [Pg.163]    [Pg.1052]    [Pg.164]    [Pg.404]    [Pg.274]    [Pg.82]    [Pg.88]    [Pg.18]    [Pg.450]    [Pg.354]    [Pg.301]    [Pg.341]    [Pg.521]    [Pg.404]    [Pg.410]    [Pg.443]    [Pg.25]    [Pg.488]    [Pg.147]    [Pg.62]    [Pg.65]    [Pg.279]    [Pg.210]    [Pg.43]    [Pg.82]   


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Acetals hydroxyl group temporary protection

Acetates, hydroxyl group protection

Benzyl groups, hydroxyl group permanent protection

Carbohydrates 1,2-hydroxyl groups, protecting group

Esters hydroxyl group, protection

Ethers hydroxyl group, protection

Hydroxyl Protecting Groups 2 Silyl Ethers

Hydroxyl group, protection

Hydroxyl group, protection

Hydroxyl group, protection Reactivity Chart

Hydroxyl groups lipase-catalyzed selective protection

Hydroxyl groups protective group strategies

Hydroxyl protecting groups, asymmetric

Hydroxyl protecting groups, asymmetric compounds

Hydroxyl-protecting groups

Hydroxyl-protecting groups

Metabolism 17/3-hydroxyl group protection, effect

Methoxymethyl hydroxyl protective group

Permanent protection, hydroxyl groups

Primary hydroxyl groups, selective protection strategies

Protecting groups for hydroxyls

Protecting groups, primary hydroxyl

Protecting groups, primary hydroxyl secondary hydroxyls

Protection for the Hydroxyl Group Esters

Protection for the Hydroxyl Group Ethers

Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols

Protection for the hydroxyl group

Protection of 3-hydroxyl groups

Protection of the carbohydrate hydroxyl groups

Reactivity charts to protect hydroxyl groups

Reactivity, hydroxyl groups, selective protection

Selective protection of hydroxyl groups

Selective protection of primary hydroxyl groups

Temporary protection, hydroxyl groups

Tetrasaccharide synthesis, hydroxyl protecting groups

Through Differentiation of Primary Hydroxyls Using Bulky Protecting Groups

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