Mesoderm-endoderm inducing factor ectoderm

Fig. 2. Mesodermal and endodermal tissues induced by the highly purified vegetalizing factor in isolated gastrula ectoderm of Triturm alpestries (sandwich method) (courtesy of Dr. H. Grunz). Abbreviations End, endoderm M, muscle and N, notochord.

In isolated ectoderm the factor induces mesodermal tissues (muscle, notochord, renal tubules, and blood cells) as well tissues which are derived from the endoderm like endodermal epithelium and intestine and, less frequently, liver, pancreas, stomach-, esophagus- and pharynx-epithelium (Fig. 2). 

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