6-Mercapto-l-hexanol

Lyttle et al. [281] used trimellitic anhydride supported on aminopropyl CPG to immobilize the ubiquitous O-dimethoxytritylated 6-mercapto-l-hexanol via the thioester linkage cleavable in ammonia (Figure 19.13). The linkage survived all... 

Mercapto-l-hexanol see fruit flavors (passion fruit, guava flavors). 

However, on the screen-printed gold electrode, the self-assembly immobilization of the oligonucleotide probe on the gold surface, the probe can be either 3 -thiol or 5 -thiol labeled with C3 or C6 linker depending on the signal substances [such as AQMS, enzyme, MB, Ru (bpy), ferrocene] and the blocking agent used [2-Mercapto-1-ethanol (MCE), 6-mercapto-l-hexanol (MCH) or 11-mercapto-l-... 

Figure 3 Schematic of a mixed thiol-derivatized single-stranded oligonucloetide/6-mercapto-l-hexanol monolayer in a solution containing the target DNA. (From Ref. 8.)...

The number of studies on self-assembled monolayers (SAMs) has grown over the past years. SAMs are molecular layers formed on a surface when it is immersed in a solution containing molecules that specifically interact with the surface. Due to the efficiency and simplicity of the self-assembly technique, the immobilization of thiol- or disulfide-modified DNA on gold electrodes was reported in the literatureSAMs at mercury electrodes were also reported by Ostatna and Palecek. Specific DNA sequence detection in clinical samples (undiluted and untreated human serum and urine samples) were performed on a ternary interface involving hexanedithiol (HDT) co-immobilized with the thiolated capture probe (SHCP) on gold surfaces, followed by the incorporation of 6-mercapto-l-hexanol (MCH) as the diluent. ... 

Auj3(SCgOH)g HAuCl /6-mercapto-l-hexanol NaBH4 Water/toluene U]... 

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