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Meralluride

Condensation of allyl isocyanate with succinimide affords the cyclic diacylurea 39. Acid hydrolysis leads to ring opening of the succinimide (40). Oxymercuration of the terminal olefin bond with mercuric acetate in methanol solution affords the diuretic meralluride (41). ... [Pg.224]

The cyclized analog of meralluride is prepared by a similar synthesis. Thus, condensation of camphoric acid (42) (obtained by oxidation of camphor) with ammonia gives the bicyclic succinimide (44). Reaction with allyl isocyanate followed by ring opening and then reaction with mercuric acetate affords the mercury derivative (45) as the acetate rather than the hydroxide as above. Reaction with sodium chloride converts that acetate to the halide (46). Displacement on mercury with the disodium salt of thioglycollic acid affords the diuretic mercaptomerine (47). ... [Pg.224]

Prajmaline bitartrate Secobarbital sodium T rioxsalen Allyl carbamide Meralluride... [Pg.1611]

Meperidine, 299, 300, 303, 306 reversed, 303 Mephenesin, 118 Mephenesin carbamate, 118 Mephenhydramine, 44 Mephenoxolone, 119 Mephentermine, 72 Mephenytoin, 246 Mephobarbital, 273 Mepivacaine, 17 Meprobamate, 218 Mequoqualone, 354 Meralluride, 224 Mercaptomerine, 224 Mesoridazine, 389 Mesterolone, 174... [Pg.483]

Alkylation of ammonia is sometimes employed in industrial processes the resulting mixture of amines is separated by distillation. The ultimate starting materials for the industrial preparation of allylamine are propene, chlorine, and ammonia. Write a series of equations showing the industrial preparation of allylamine from these starting materials. (Allylamine has a number of uses, including the preparation of the diuretic drugs meralluride and mercaptomerin.)... [Pg.936]

Butanoic acid, 4-((( 2-methoxypropyl)amino)carbonyl)-amino)-4-OXO-, mercury complex Dilurgen N-((3-(Hydroxymercuri)-2-methoxypropyl)carbamoyl)-succlnamic acid and theophylline Meralluride Meralluridum Meralurida Mercardan Mercuhydrin Mercurate(l-), (3-((((3-carboxylato-1-oxopropyl)amino)-... [Pg.386]

Examples Chlormerodrin Hg 197 Meralluride Mercaptomerin sodium Merethoxylline procaine Mersalyl and Mercumatilin sodium. [Pg.439]

Meralluride is employed for the treatment of oedema secondary to congestive heart failure, the nephrotic state of glomerulonephritis and hepatic cirrhosis. [Pg.441]

The uses of mercaptomerin sodium are similar to those of meralluride. [Pg.442]

See other pages where Meralluride is mentioned: [Pg.929]    [Pg.603]    [Pg.929]    [Pg.442]    [Pg.947]    [Pg.947]    [Pg.948]    [Pg.461]    [Pg.12]    [Pg.204]    [Pg.195]    [Pg.2181]    [Pg.2181]    [Pg.2182]    [Pg.260]    [Pg.176]    [Pg.872]    [Pg.59]    [Pg.386]    [Pg.742]    [Pg.998]    [Pg.440]    [Pg.441]    [Pg.947]    [Pg.947]    [Pg.948]   
See also in sourсe #XX -- [ Pg.224 ]

See also in sourсe #XX -- [ Pg.3 , Pg.67 ]

See also in sourсe #XX -- [ Pg.59 ]

See also in sourсe #XX -- [ Pg.439 , Pg.440 , Pg.441 , Pg.442 , Pg.443 ]

See also in sourсe #XX -- [ Pg.143 , Pg.422 ]



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Allyl carbamide Meralluride

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