Membrane Rate-Limiting Transport Hydrophilic Molecules

Membrane Rate-Limiting Transport (Hydrophilic Molecules) 

The dashed curves in Fig. 3.4 were calculated using Eq. (24), without consideration of the resistance of the ABL, and represent the membrane part of the overall 

(24) is that of a horizontal line, and for pH pKj, Eq. (24) is that of a diagonal line, with a slope of -1. It is possible to determine the Pq and pfQ of a molecule from the log Pe - pH data when the transport is primarily membrane-limited. 

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