Melicope

Furoquinolones Melicope confuse SiOj CHCI3 + MeOH Identification, biological activity 82... 

Chen, J.-J., Duh, C.-Y., Huang, H.-Y. and Chen, I.-S. 2003. Furoquinoline alkaloids and cytotoxic constituents from the leaves of Melicope semecarpifolia. Planta Medica, 69 542-546. 

Chen, K. S., Chang, Y. L., Teng, C. M., Chen, C. F. and Wu, Y. C. 2000. Furo-quinolines with antiplatelet aggregation activity from leaves of Melicope confuse. Planta Medica, 66 80-81. 

Melicope subunifoliolata Meliternatin (3,5-dimethoxy-3, 4, 6,7- Strong feeding deterrent activity 370... 

Ho, S.H. et al., Meliternatin a feeding deterrent and larvicidal polyoxygenated flavone from Melicope subunifoliolata. Phytochemistry, 62, 1121, 2003. 

These compounds are almost exclusively accumulated in aerial parts and leaves from genera of the Rutaceae such as Bosistoa, Boronia, and Melicope, and rarely in Euodia and Zanthox-ylum. There is a strong tendency towards prenylation at the 7-OH or 4 -OH group. From aerial parts of Boronia coerulescens, a derivative with 3,4 -(9-prenylation was also described (compound 130, Table 12.4). Similarly, only one C-6-(9-derivative was reported from the aerial parts of Melicope. Two 7-epoxy derivatives have already been listed in the previous survey. Combination with methylenedioxy substitution is less frequent, concerning a few sources of Rutaceae and Asteraceae only. Probably, these constituents are partly accumulated externally. 

Sultana, N., Hartley, T.G., and Waterman, P.G., Two novel prenylated flavones from the aerial parts of Melicope micrococca. Phytochemistry, 50, 1249, 1999. 

Simonsen, H.T. et al., Methylenedioxy- and methoxyflavones from Melicope coodeana syn. Euodia simplex. Phytochemistry, 60, 817, 2002. 

Wang, E. et al.. The crystal structure of the dimorphic forms of a new flavonoid from the Australian tree Melicope elleryana, Aust. J. Chem., 54, 739, 2001. 

Higa, M. et al., Flavonoid constituents of Melicope triphylla, Yakugaku Zasshi, 110, 822, 1990. 

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