Meiosis oocytes

Kanki, J. P, and Donoghue, D. J. (1991). Progression from meiosis I to meiosis II in Xenopus oocytes requires de novo translation of the mos" protooncogene. Proc. Natl. Acad. Sci. USASS 5794-5798. 

Posada, J., and Cooper, J. A. (1992). Requirements for phosphorylation of MAP kinase during meiosis in Xenopus oocytes. Science 255 212-215. 

Swenson, K. I., Farrell, K. M., and Ruderman, J. V. (1986). The clam embryo protein cyclin A induces entry into M phase and the resumption of meiosis in Xenopus oocytes. Cell 47 861-870. 

Figure 1. Expression of c-mos in mouse oocytes, c-mos is transcribed during oocyte growth and transcripts with short poly(A) tails are accumulated in fully-grown germinal vesicle (GV) stage oocytes. These transcripts are polyadenylated and translated following the resumption of meiosis and then degraded following fertilization and cleavage to the two-cell stage.

Figure 2. Role of c-mos in meiosis of mouse oocytes. Mouse oocytes microinjected with antisense c-mos oligonucleotides fail to progress from meiosis I to meiosis II, instead reforming nuclei following polar body extrusion (O Keefe et al., 1989).

Gross SD, Schwab MS, Lewellyn AL, Mailer JL 1999 Induction of metaphase arrest in cleaving Xenopus embryos by the protein kinase p90Rsk. Science 286 1365—1367 Gross SD, Schwab MS, Taieb FE, Lewellyn AL, Qian Y-W, Mailer JL 2000 The critical role of the MAP kinase pathway in meiosis II in Xenopus oocytes is mediated by p90Rsk. Curr Biol 10 430-438... 

Verlhac MH, de Pennart H, Maro B, Cobb MH, Clarke HJ 1993 MAP kinase becomes stably activated at metaphase and is associated with microtubule-organizing centers during meiotic maturation of mouse oocytes. Dev Biol 158 330-340 Verlhac MH, Kubiak JZ, Clarke HJ, Maro B 1994 Microtubule and chromatin behavior follow MAP kinase activity but not MPF activity during meiosis in mouse oocytes. Development 120 1017-1025... 

Ciemerych MA, Kubiak JZ 1998 Cytostatic activity develops during Meiosis I in oocytes of LT/Sv mice. Dev Biol 200 198-211... 

The presence of Li+ results in the reversible inhibition of the hormone-induced meiotic maturation of starfish oocytes [226], and also reverses the inhibitory effect of forskolin on the spontaneous resumption of meiosis in uncoated mouse oocytes in vitro [227]. In the latter case, the effect of Li+ upon the adenylate cyclase response occurs only after it has been activated by forskolin. 

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