Medicated confectionery bases

Base for medicated confectionery coating agent granulating agent sweetening agent tablet and capsule diluent. 

Petrolatum is mainly used in topical pharmaceutical formulations as an emollient-ointment base it is poorly absorbed by the skin. Petrolatum is also used in creams and transdermal formulations and as an ingredient in lubricant formulations for medicated confectionery together with mineral oil. 

When sucrose is used as a base for medicated confectionery, the cooking process, at temperatures rising from 110 to 145°C, causes some inversion to form dextrose and fructose (invert sugar). The fructose imparts stickiness to confectionery but prevents cloudiness due to graining. Inversion is accelerated particularly at temperatures above 130°C and by the presence of acids. 

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