Medical/research ethics decision-making

The basic aim of medical research is to improve clinical practice, and this should be evidence based, if possible. Clinically relevant research evidence may relate to basic medical science, but it especially relates to patient-centered cUnical research, e.g., to the study of the accuracy and precision of diagnostic tests, the power of prognostic markers, and the efficacy and safety of therapeutic, rehabilitative, and preventive regimens. New evidence from clinical research at the same time invalidates previously accepted diagnostic tests and treatments and replaces them with new ones that are more powerful, more accurate, more efficacious, and safer [1]. Ethical decision making is based on the Declaration of Helsinki,... 

Regardless of whether it is a clinical trial or analytical investigation of a sample (e.g., plasma), the subjects of medical research are human beings. Ethical considerations are therefore important they influence decision making and are well regulated in the medical field. 

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